Thermo Fisher Scientific WRN Polyclonal Antibody
WRN 단백질을 인식하는 Rabbit Polyclonal 항체로, 인간 시료에 반응합니다. ICC/IF 실험에 적합하며, 고순도의 Affinity chromatography로 정제되었습니다. 0.3 mg/mL 농도의 액상 형태로 제공되며, 장기 보관 시 -20°C에서 안정적으로 유지됩니다.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific WRN Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence (range: 190–304). Recombinant protein control fragment: Product #RP-110122 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_3092196 |
Product Specific Information
Immunogen sequence:
LKDKSIRCSN WSKFPLTEDQ KLYAATDAYA GFIIYRNLEI LDDTVQRFAI NKEEEILLSD MNKQLTSISE EVMDLAKHLP HAFSKLENPR RVSILLKDIS ENLYSLRRMI IGSTN
Antigen sequence identity:
- Mouse: 66%
- Rat: 65%
Target Information
This gene encodes a member of the RecQ subfamily and the DEAH (Asp-Glu-Ala-His) subfamily of DNA and RNA helicases. DNA helicases are involved in many aspects of DNA metabolism, including transcription, replication, recombination, and repair.
This protein contains a nuclear localization signal in the C-terminus and shows a predominant nucleolar localization. It possesses intrinsic 3′ to 5′ DNA helicase activity and also functions as a 3′ to 5′ exonuclease.
Based on interactions between this protein and the Ku70/80 heterodimer in DNA end processing, it may be involved in the repair of double-strand DNA breaks.
Defects in this gene cause Werner syndrome, an autosomal recessive disorder characterized by premature aging.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.