Thermo Fisher Scientific WISP2 Polyclonal Antibody
WISP2 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot에 적합합니다. 인간 단백질에 반응하며, 액상 형태로 제공됩니다. 친화 크로마토그래피로 정제되었으며, PBS와 글리세롤 버퍼에 보존됩니다. 연구용으로만 사용 가능합니다.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific WISP2 Polyclonal Antibody
Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide sequence around aa.242–246 (G-R-S-P-Q) derived from Human WISP2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2635146 |
Product Specific Information
This antibody detects endogenous levels of total WISP2 protein.
Target Information
WISP2 is a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a cysteine-rich, glycosylated signaling protein family that mediates diverse developmental processes.
CTGF family members have four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain, and C-terminal cystine knot-like (CT) domain.
WISP2 lacks the CT domain, which is implicated in dimerization and heparin binding. It shares 72% amino acid identity with the mouse protein.
This gene may act downstream in the WNT1 signaling pathway relevant to malignant transformation. Its expression is reduced in colon tumors, whereas other WISP members are overexpressed. WISP2 is highly expressed in bone tissue and may play a role in modulating bone turnover.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.