Thermo Fisher Scientific CaV1.3 Monoclonal Antibody (S48), PE
CaV1.3 단백질을 인식하는 Mouse monoclonal 항체로, PE 형광 표지되어 있습니다. Western blot, IHC, ICC, IP 등 다양한 응용에 적합하며, Human, Mouse, Rat 시료에서 반응합니다. 단백질 G 정제, 보존제 무첨가, 4°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1:1,000 | |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000 | |
| Immunocytochemistry (ICC/IF) | 1:100 | |
| Immunoprecipitation (IP) | Assay-dependent | |
| Antibody Microarray (AM) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | S48 |
| Immunogen | Fusion protein amino acids 859–875 of rat Cav1.3 |
| Conjugate | PE (R-Phycoerythrin) |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | 95.64 mM phosphate / 2.48 mM MES, pH 7.4, with 0.5 M EDTA |
| Contains | No preservative |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2931848 |
Additional Formats Available
- Unconjugated (MA5-27716)
- APC (MA5-45391)
- FITC (MA5-45392)
- PerCP (MA5-45393)
- Custom conjugation available upon request
Product Specific Information
1 µg/mL of MA5-45394 was sufficient for detection of Cav1.3 in 10 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. Detects approximately 250 kDa. No cross-reactivity against Cav1.2.
Target Information
CACNA1D (also known as PASNA, SANDD, or Cav1.3) encodes the alpha-1D subunit of the voltage-dependent calcium channel complex. These channels mediate calcium ion entry into excitable cells and are involved in processes such as muscle contraction, neurotransmitter release, and gene expression. The alpha-1 subunit forms the channel pore, while beta, alpha-2/delta, and gamma subunits modulate channel function. Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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