Thermo Fisher Scientific CaV1.3 Monoclonal Antibody (S48), PerCP
CaV1.3 단백질을 검출하기 위한 PerCP 결합 단클론 항체로, WB, IHC, ICC 등 다양한 응용에 사용 가능. 인간, 마우스, 랫트 반응성. 단클론 IgG2a, kappa 형태로 높은 특이성과 재현성 제공. 형광 특성 482/675 nm, 연구용 전용.
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Thermo Fisher Scientific CaV1.3 Monoclonal Antibody (S48), PerCP
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Immunoprecipitation (IP) | Assay-dependent |
| Antibody Microarray (AM) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | S48 |
| Immunogen | Fusion protein amino acids 859–875 of rat Cav1.3 |
| Conjugate | PerCP |
| Excitation / Emission Max | 482 / 675 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | 95.64 mM phosphate / 2.48 mM MES, pH 7.4, with 0.5 M EDTA |
| Contains | No preservative |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2931847 |
Available Formats
Product Specific Information
1 µg/mL of MA5-45393 was sufficient for detection of Cav1.3 in 10 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. Detects approximately 250 kDa. No cross-reactivity against Cav1.2.
Target Information
CACNA1D (also known as PASNA, SANDD, or Cav1.3) encodes the alpha-1D subunit of voltage-dependent calcium channels. These channels mediate calcium ion entry into excitable cells and regulate processes such as muscle contraction, hormone or neurotransmitter release, and gene expression. Calcium channels are multisubunit complexes composed of alpha-1, beta, alpha-2/delta, and gamma subunits. The alpha-1 subunit forms the pore and determines channel properties, while auxiliary subunits modulate activity. Multiple transcript variants encoding different isoforms exist for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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