Thermo Fisher Scientific CaV1.3 Monoclonal Antibody (S48), FITC
CaV1.3 단백질을 특이적으로 인식하는 FITC 결합 단클론 항체로, Western blot, IHC, ICC/IF, IP 등 다양한 응용에 사용 가능. Human, Mouse, Rat 시료에 반응하며, 498/517 nm 형광 특성. 4°C 암소 보관, 단백질 G 정제, 보존제 무첨가.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Immunoprecipitation (IP) | Assay-dependent |
| Antibody Microarray (AM) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | S48 |
| Immunogen | Fusion protein amino acids 859–875 of rat Cav1.3 |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | 9.1 mM sodium bicarbonate/PBS (pH 7.4), with 640.91 mM DMSO, 136.36 mM ethanolamine |
| Contains | No preservative |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2931846 |
Additional Formats
- Unconjugated (MA5-27716)
- APC (MA5-45391)
- PE (MA5-45394)
- PerCP (MA5-45393)
- Request custom conjugation available
Product Specific Information
1 µg/mL of MA5-45392 was sufficient for detection of Cav1.3 in 10 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. Detects approximately 250 kDa. No cross-reactivity against Cav1.2.
Target Information
CACNA1D (also known as PASNA, SANDD, or Cav1.3) encodes the alpha-1D subunit of voltage-dependent calcium channels. These channels mediate calcium ion entry into excitable cells and regulate processes such as muscle contraction, hormone or neurotransmitter release, and gene expression. The alpha-1 subunit forms the channel pore, while beta, alpha-2/delta, and gamma subunits modulate channel activity. Multiple transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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