Thermo Fisher Scientific Alpha-1-Antichymotrypsin (SERPINA3) (Histiocytoma Marker) Monoclonal Antibody (AACT/1451, AACT/1452)
Alpha-1-Antichymotrypsin 단백질을 표적으로 하는 인간 반응성 단클론 항체. IHC(P) 및 IHC(PFA) 실험에 적합하며, Alzheimer’s disease 연구 등에서 유용. Protein A/G 정제, 1 mg/mL 농도의 액상 형태, 보존제 없음. -20°C 보관.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | AACT/1451, AACT/1452 |
| Immunogen | Recombinant human Antichymotrypsin (AACT) protein fragment (around aa 49–187) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
SERPINA encodes Alpha 1-ACT, an early-stage acute-phase plasma protein and a serpin that preferentially inactivates chymotrypsin, cathepsin G, and chymase.
Alpha-1-ACT, a serine protease inhibitor, is closely associated with amyloid plaques in Alzheimer’s disease (AD) and in normal aged human and monkey brains.
Regulation of serine proteases and their inhibitors plays an important role in neuromuscular differentiation.
Prostate specific antigen (PSA), a chymotrypsin-like serine protease, is predominantly complexed to Alpha-1-ACT.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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