Thermo Fisher Scientific HP1 beta Monoclonal Antibody (1MOD-1A9)

Thermo Fisher Scientific HP1 beta Monoclonal Antibody (1MOD-1A9)

Applications and Tested Dilution

Product Specifications

Product Specific Information

MA3-053 detects HP1-beta in human samples.
MA3-055 has been successfully used in Western blot, immunofluorescence, ELISA, and ChIP applications.
Immunogen is a HP1-beta recombinant mouse.

Target Information

This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in heterochromatin and associated with centromeres. It contains a single N-terminal chromodomain that binds histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain responsible for homodimerization and interaction with chromatin-associated nonhistone proteins.
The protein may play an important role in epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants encoding the same protein have been identified.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.