Thermo Fisher Scientific Histone H2A Monoclonal Antibody (10HH2-2G12)
Human Histone H2A를 인식하는 Mouse Monoclonal Antibody로, Western blot 및 ELISA에 적합. 합성 펩타이드(aa 115-124)를 면역원으로 사용. Unconjugated 형태이며 ascites buffer에 0.05% sodium azide 포함. -20°C에서 보관, 연구용 전용.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | - |
| Immunocytochemistry (ICC/IF) | - | 1 publication |
| ELISA | 1:500 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 10HH2-2G12 |
| Immunogen | Synthetic peptide: VLLPKKTESH (aa 115–124 of human H2A) conjugated to ovalbumin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Ascites |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2609728 |
Product Specific Information
MA3-047 detects Histone H2A in human samples.
It has been successfully used in Western blot and ELISA applications.
The immunogen is a synthetic peptide conjugated to ovalbumin corresponding to residues 115–124 of human Histone H2A, which is highly conserved across multiple species.
Target Information
Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fibers in eukaryotes.
Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units called nucleosomes.
The linker histone H1 interacts with linker DNA between nucleosomes and functions in chromatin compaction.
This gene is intronless and encodes a member of the histone H4 family. Transcripts lack polyA tails but contain a palindromic termination element.
It is located within the large histone gene cluster on chromosome 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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