Thermo Fisher Scientific Histone H2A Monoclonal Antibody (10HH2-2G12)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

-

Immunocytochemistry (ICC/IF)

-

View 1 publication 1 publication

ELISA (ELISA)

1:500

-

Product Specifications

Species Reactivity

Human

Published species

Human

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

10HH2-2G12

Immunogen

Synthetic peptide: VLLPKKTESH corresponding to amino acids 115-124 of human H2A. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Histone H2A,uniProtId:P0C0S8-1,ncbiNodeId:9606,antigenRange:115-124,antigenLength:130,antigenImageFileName:MA3-047_Histone_H2A_P0C0S8-1_House_mouse.svg,antigenImageFileNamePDP:MA3-047_Histone_H2A_P0C0S8-1_House_mouse_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

Conc. Not Determined

Storage buffer

ascites

Contains

0.05% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2609728

Product Specific Information

MA3-047 detects Histone H2A in Human samples.

MA3-047 has been succesfully used in western blot and ELISA applications.

Immunogen is a synthetic peptide conjugated to ovalbumin corresponding to residues 115-124 of Human Histone H2A, which is highly conserved across multiple species.

Target Information

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.