Thermo Fisher Scientific CDK9 Polyclonal Antibody
CDK9 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal antibody. Western blot에 적합하며 Human, Mouse, Rat 반응성. 항원 친화 크로마토그래피로 정제, 고순도(>95%) 제품. 세포 성장 및 전사 조절 연구용.
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Thermo Fisher Scientific CDK9 Polyclonal Antibody
Applications
- Western Blot (WB): Tested dilution 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to residues in Human CDK9 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2803507 |
Product Specific Information
Purity is > 95% by SDS-PAGE.
Target Information
CDK9 is a serine/threonine kinase that forms an active holoenzyme complex with CyclinT1, playing a key role in regulating the eukaryotic cell cycle. It regulates cytokine-inducible transcription networks by facilitating promoter recognition of target transcription factors and promotes RNA synthesis in genetic programs for cell growth, differentiation, and viral pathogenesis.
The CDK9/cyclin-K complex also exhibits kinase activity towards CTD of RNAPII and can substitute for CDK9/cyclin-T P-TEFb in vitro. Chronic activation of CDK9 leads to cardiac myocyte enlargement and predisposition to heart failure.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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