Thermo Fisher Scientific FCAR Polyclonal Antibody
Thermo Fisher Scientific의 FCAR Polyclonal Antibody는 인간, 마우스, 랫트 시료에 반응하는 고순도(>95%) 항체입니다. Western blot에 1:500~1:1,000 희석으로 사용 가능하며, IgA Fc 수용체 연구에 적합합니다. 항원 친화 크로마토그래피로 정제된 고품질 연구용 항체입니다.
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Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to residues in Human FCAR |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2803505 |
Product Specific Information
- Purity is >95% by SDS-PAGE.
Target Information
The FCAR gene belongs to the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA.
This receptor is a transmembrane glycoprotein expressed on myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils.
It mediates immunologic responses to pathogens by interacting with IgA-opsonized targets and triggering defense mechanisms including:
- Phagocytosis
- Antibody-dependent cell-mediated cytotoxicity
- Release of inflammatory mediators
Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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