Thermo Fisher Scientific NMDAR1 Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

This antibody is predicted to react with canine, chicken, human, non-human primate, and Xenopus based on 100% sequence homology.
In Western blot, this antibody detects an approximately 100 kDa protein representing the NR1 N1 splice variant from rat brain homogenate. It shows no cross-reactivity with the NR1 C1, C2, or C2 splice variants.
Reconstitute with 50 µL of PBS. After reconstitution, aliquot and store at -20°C.

Target Information

NMDAR1 encodes a critical subunit of N-methyl-D-aspartate (NMDA) receptors, which are members of the glutamate receptor channel superfamily. These heteromeric protein complexes form ligand-gated ion channels that play a key role in synaptic plasticity, memory, and learning.
Cell-specific factors regulate the expression of different isoforms, contributing to functional diversity. Alternatively spliced transcript variants have been described.

For Research Use Only. Not for use in diagnostic procedures or resale without express authorization.