Thermo Fisher Scientific NMDAR1 Polyclonal Antibody
NMDAR1 단백질을 인식하는 Rabbit Polyclonal 항체로, WB 및 IHC에 적합합니다. Rat GRIN1 N1 splice variant에 특이적으로 반응하며, 높은 특이성과 재현성을 제공합니다. 연구용으로만 사용되며 -20°C에서 보관합니다.
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- OPA104011
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (IHC) | 1:1,000–1:2,000 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:1,000–1:2,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acid residues specific to the NR1 subunit of rat GRIN1, N1 splice variant insert conjugated to KLH |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_325646 |
Product Specific Information
This antibody is predicted to react with canine, chicken, human, non-human primate, and Xenopus based on 100% sequence homology.
In Western blot, this antibody detects an approximately 100 kDa protein representing the NR1 N1 splice variant from rat brain homogenate. It shows no cross-reactivity with the NR1 C1, C2, or C2 splice variants.
Reconstitute with 50 µL of PBS. After reconstitution, aliquot and store at -20°C.
Target Information
NMDAR1 encodes a critical subunit of N-methyl-D-aspartate (NMDA) receptors, which are members of the glutamate receptor channel superfamily. These heteromeric protein complexes form ligand-gated ion channels that play a key role in synaptic plasticity, memory, and learning.
Cell-specific factors regulate the expression of different isoforms, contributing to functional diversity. Alternatively spliced transcript variants have been described.
For Research Use Only. Not for use in diagnostic procedures or resale without express authorization.
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