Thermo Fisher Scientific NMDAR1 Polyclonal Antibody
NR1 서브유닛 특이적 합성 펩타이드로 제작된 Rabbit Polyclonal 항체. WB 및 IHC에 사용 가능하며 Rat, Mouse에 반응. NR1 C1 splice variant 검출에 특이적이며 교차반응 없음. 동결건조 형태로 제공되며 -20°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (IHC) | 1:1,000–1:2,000 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:1,000–1:2,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acid residues specific to the NR1 subunit of rat GRIN1, C1 splice variant insert conjugated to KLH |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Whole serum, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_325647 |
Product Specific Information
- Predicted to react with bovine, canine, human, and non-human primate based on 100% sequence homology.
- In Western blot, detects an ~100 kDa protein representing the NR1 C1 splice variant from rat brain homogenate.
- No cross-reactivity with NR1 N1, C2, or C2 splice variants.
- Reconstitute with 50 µL of PBS.
Target Information
NMDAR1 encodes a protein that is a critical subunit of N-methyl-D-aspartate (NMDA) receptors, members of the glutamate receptor channel superfamily. These are heteromeric protein complexes forming ligand-gated ion channels. The subunits play key roles in synaptic plasticity, underlying memory and learning. Expression of different isoforms is controlled by cell-specific factors, contributing to functional diversity. Alternatively spliced transcript variants have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송 정보
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