Thermo Fisher Scientific Synapsin 1 Polyclonal Antibody
Synapsin 1 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, WB 및 IHC에 적합합니다. 뇌 조직 내 시냅스 소포 단백질 검출에 유용하며, -20°C에서 보관합니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- OPA104001
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific Synapsin 1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | - |
| Immunohistochemistry (IHC) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Native protein purified from bovine brain |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_325645 |
Product Specific Information
In Western blot, this antibody detects approximately 77 kDa and 80 kDa proteins representing synapsin I alpha and synapsin I beta respectively, in rat brain homogenate.
Immunohistochemical staining of synapsin 1 alpha and 1 beta in human brain with OPA1-04001 yields a pattern consistent with cytoplasmic vesicle staining.
Target Information
SYN1 (synapsin 1) is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins that associate with the cytoplasmic surface of synaptic vesicles.
Family members are characterized by common protein domains and are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases.
Synapsin 1 plays a role in regulation of axonogenesis and synaptogenesis. It serves as a substrate for several different protein kinases, and phosphorylation may function in the regulation of this protein in the nerve terminal.
Mutations in this gene may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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