Thermo Fisher Scientific NMDAR1 Polyclonal Antibody
NMDAR1 단백질을 인식하는 Rabbit Polyclonal 항체로, WB 및 IHC에 적합합니다. Mouse와 Rat 시료에 반응하며 human에도 예측 반응합니다. 합성 펩타이드 면역원 기반으로 제작되었으며, 동결건조 형태로 제공됩니다.
- 카탈로그번호
- OPA104013
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (IHC) | 1:1,000–1:2,000 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:1,000–1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acid residues specific to the NR1 subunit of rat GRIN1, C2 splice variant insert conjugated to KLH |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_325648 |
Product Specific Information
This antibody is predicted to react with human based on 100% sequence homology.
In Western blot, this antibody detects an ~100 kDa protein representing the NR1 C2 splice variant from rat brain homogenate. It shows no cross-reactivity with the NR1 N1, C1, or C2 splice variants.
Reconstitute with 50 µL of PBS.
Target Information
NMDAR1 encodes a protein that is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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