Thermo Fisher Scientific Cytochrome C Monoclonal Antibody (6H2.B4), Alexa Fluor 647
Cytochrome C 단백질을 인식하는 Mouse monoclonal 항체로 Alexa Fluor 647로 표지됨. 인간, 마우스, 랫, 토끼, 초파리에 반응. 세포 내 Cytochrome C 검출 및 apoptosis 연구에 적합. 1 mg/mL 농도의 액상 형태로 제공.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1–10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Fruit fly, Human, Mouse, Rabbit, Rat |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 6H2.B4 |
| Immunogen | Rat cytochrome C |
| Conjugate | Alexa Fluor™ 647 |
| Excitation / Emission Max | 650 / 671 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4, with 1 mg/mL BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2663052 |
Additional Formats
- Unconjugated (Cat. No. 33-8200)
- Alexa Fluor 488 (Cat. No. MA3-38200-A488)
- Alexa Fluor 555 (Cat. No. MA3-38200-A555)
- Custom conjugation available upon request
Product Specific Information
This antibody reacts with native Cytochrome C, but does not recognize denatured Cytochrome C.
It recognizes a region near amino acid 62 of rat Cytochrome C.
Target Information
Cytochrome C is an electron-transporting protein located in the mitochondrial intermembrane space, playing a key role in oxidative phosphorylation and ATP production.
Upon apoptotic stimulation, Cytochrome C is released into the cytosol, where it binds apoptotic protease activating factor, leading to activation of procaspase 9 and subsequently caspase 3 — a major effector of apoptosis.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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