Thermo Fisher Scientific ATG4D Polyclonal Antibody
ATG4D 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(P) 실험에 적합. 합성 펩타이드(aa 10-50)를 면역원으로 사용. 동결건조 형태로 제공되며, 장기 보관 시 -20°C 권장. 연구용으로만 사용 가능.
- 카탈로그번호
- OSA00032W-150UL
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,500–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from aa region 10–50 of human ATG4D conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 150 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: ATG4D.
Target Information
Atg4D (autophagy-related gene 4D), also known as APG4D or AUTL4, is a 474 amino acid protein that localizes to the cytoplasm and belongs to the C-54 family of cysteine proteases.
It is expressed predominantly in skeletal muscle and testis. Atg4D functions as a cysteine protease required for autophagy, specifically cleaving the C-terminal region of target proteins to enable binding to autophagosomes.
The enzymatic activity of Atg4D is inhibited by N-ethylmaleimide, a thiol-reactive compound that modifies cystine residues in proteins and peptides.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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