Thermo Fisher Scientific ATG4D Polyclonal Antibody
Rabbit polyclonal antibody recognizing mouse ATG4D protein for use in WB and IHC. Lyophilized form with whole serum buffer, unconjugated type. Specific for autophagy-related ATG4D detection in research applications. Storage at 4°C short term or -20°C l...
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Applications
Western Blot (WB)
- Tested Dilution: 1:200–1:2,000
Immunohistochemistry (IHC)
- Tested Dilution: 1:200–1:2,000
Miscellaneous (PubMed)
- Publication available: View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from mouse ATG4D conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 150 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: ATG4D.
Target Information
Atg4D (autophagy-related gene 4D), also known as APG4D or AUTL4, is a 474 amino acid protein localized in the cytoplasm and belongs to the C-54 family of cysteine proteases. It is predominantly expressed in skeletal muscle and testis. Atg4D acts as a cysteine protease required for autophagy, specifically cleaving the C-terminal region of target proteins to enable their binding to autophagosomes. Its enzymatic activity is inhibited by N-ethylmaleimide, a thiol-reactive compound that modifies cystine residues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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