Thermo Fisher Scientific ATG4D Polyclonal Antibody
ATG4D 단백질을 인식하는 Sheep 폴리클로날 항체로, Western blot과 IHC에 사용 가능. 합성 펩타이드 면역원으로 제작되어 높은 특이성과 재현성 제공. 동결건조 형태로 공급되며, 4°C 또는 -20°C에서 안정적으로 보관 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200–1:3000 |
| Immunohistochemistry (IHC) | 1:200–1:3000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Sheep / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from human ATG4D |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1089691 |
Product Specific Information
Reconstitute with 150 µL of distilled water.
Target Information
Atg4D (autophagy-related gene 4D), also known as APG4D or AUTL4, is a 474 amino acid cytoplasmic protein belonging to the C-54 family of cysteine proteases. It is predominantly expressed in skeletal muscle and also present in testis. Atg4D acts as a cysteine protease required for autophagy, specifically cleaving the C-terminal region of target proteins to enable their binding to autophagosomes. Its enzymatic activity is inhibited by N-ethylmaleimide, a thiol-reactive compound that modifies cystine residues in proteins and peptides.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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