Thermo Fisher Scientific PDHB Polyclonal Antibody
Thermo Fisher Scientific의 PDHB Polyclonal Antibody는 인간 PDHB 단백질을 인식하는 토끼 유래 IgG 항체입니다. Western blot과 IHC(파라핀) 분석에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS, 글리세롤, 나트륨 아지드 포함 용액 형태로 제공됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
- Publications: References
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:20–1:50
- Publications: References
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PDHB. Recombinant protein control fragment (Product #RP-96432) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2645334 |
Product Specific Information
- Immunogen sequence:
MAGLRPICEF MTFNFSMQAI DQVINSAAKT YYMSGGLQPV PIVFRGPNGA SAGVAAQHSQ CFAAWYGHCP GLKVVSPWNS EDAKG - Highest antigen sequence identity to the following orthologs:
Mouse – 99%, Rat – 99%
Target Information
PDHB (Pyruvate dehydrogenase E1 component subunit beta, mitochondrial), also known as PHE1B, is a mitochondrial enzyme that is part of the pyruvate dehydrogenase multienzyme complex (PDH). It catalyzes the first reaction of oxidative decarboxylation converting pyruvate to acetyl-CoA and CO₂.
Defects in PDHB cause pyruvate dehydrogenase E1-beta deficiency (PDHBD).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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