Thermo Fisher Scientific SCN11A Polyclonal Antibody
인간 SCN11A 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체. IHC(P) 실험에 적합하며, 항원 친화 크로마토그래피로 정제됨. PBS 및 글리세롤 저장 버퍼 포함, 단기 4°C 보관 및 장기 -20°C 보관 권장.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific SCN11A Polyclonal Antibody
Applications
- Immunohistochemistry (Paraffin) (IHC (P))
Tested Dilution: 1:20–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SCN11A (Product #RP-96436) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2647013 |
Product Specific Information
Immunogen sequence:
EERNGNLEGE ARKTKVQLAL DRFRRAFCFV RHTLEHFCHK WCRKQNLPQQ KEVAGGCAAQ SKDIIPLVMEHighest antigen sequence identity to orthologs:
- Mouse: 53%
- Rat: 56%
Target Information
Epithelial sodium channels are amiloride-sensitive members of the Degenerin/epithelial sodium channel (Deg/ENaC) superfamily of ion channels. These channels share structural organization with two short intracellular termini, two transmembrane segments, and a large extracellular loop containing a conserved cysteine-rich region.
ENaC isoforms (alpha, beta, gamma) are expressed in kidney, lung, and colon, playing essential roles in sodium and fluid balance. ENaC mediates aldosterone-dependent sodium reabsorption in the distal nephron, regulating blood pressure.
ENaC function is partly regulated through interaction with the CFTR chloride ion channel. Mutations in ENaC subunits can lead to hypertension (Liddle’s syndrome) or pseudohypoaldosteronism (PHA-1).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.