Thermo Fisher Scientific PCGF4 Monoclonal Antibody (4E10-1C5)
Human PCGF4 단백질을 표적으로 하는 Mouse IgG1 단클론 항체로 Western blot 및 ELISA에 사용 가능. GST 태그가 포함된 full-length recombinant immunogen으로 제작. 보존제 무첨가 PBS 용액 형태, -20°C 보관 권장. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 1 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4E10-1C5 |
| Immunogen | PCGF4 (AAH11652, 1–326 a.a) full-length recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MHRTTRIKIT ELNPHLMCVL CGGYFIDATT IIECLHSFCK TCIVRYLETS KYCPICDVQV HKTRPLLNIR SDKTLQDIVY KLVPGLFKNE MKRRRDFYAA HPSADAANGS NEDRGEVADE DKRIITDDEI ISLSIEFFDQ NRLDRKVNKD KEKSKEEVND KRYLRCPAAM TVMHLRKFLR SKMDIPNTFQ IDVMYEEEPL KDYYTLMDIA YIYTWRRNGP LPLKYRVRPT CKRMKISHQR DGLTNAGELE SDSGSDKANS PAGGIPSTSS CLPSPSTPVQ SPHPQFPHIS STMNGTSNSP SGNHQSSFAN RPRKASVNGS SATSSG
Target Information
Component of the Polycomb group (PcG) multiprotein PRC1 complex, which maintains transcriptional repression of many genes, including Hox genes, during development.
The PRC1 complex acts via chromatin remodeling and histone modification, mediating monoubiquitination of histone H2A at Lys-119, leading to heritable changes in chromatin expressibility.
Within the PRC1 complex, PCGF4 is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
For Research Use Only.
Not for use in diagnostic procedures or resale without express authorization.
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