Thermo Fisher Scientific PITX2 Monoclonal Antibody (OTI1H10), TrueMAB

Applications

Western Blot (WB)

• Tested Dilution: 1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

PITX2 is a member of the RIEG/PITX homeobox family within the bicoid class of homeodomain proteins. It functions as a transcription factor regulating procollagen lysyl hydroxylase gene expression and contributes to terminal differentiation of somatotroph and lactotroph cell phenotypes.
This protein plays roles in the development of the eye, tooth, and abdominal organs, and in transcriptional regulation of prolactin activity.
Mutations are associated with Axenfeld-Rieger syndrome, iridogoniodysgenesis syndrome, and Peters anomaly. Homologous proteins in other species are involved in left-right asymmetry determination during development.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.