Thermo Fisher Scientific TFE3 Recombinant Rabbit Monoclonal Antibody (ARC1829)
TFE3 단백질을 인식하는 재조합 토끼 단일클론 항체로, Western blot, IHC, ELISA 등 다양한 응용에 적합합니다. 인간, 마우스, 랫트 반응성을 가지며, 고순도의 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific TFE3 Recombinant Rabbit Monoclonal Antibody (ARC1829)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:4,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:400 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC1829 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 191–440 of human TFE3 (P19532) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.8 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897741 |
Product Specific Information
Positive Samples: NIH/3T3, C6, HeLa
Immunogen Sequence:
LQQARRQQVK QYLSTTLGPK LASQALTPPP GPASAQPLPA PEAAHTTGPT GSAPNSPMAL LTIGSSSEKE IDDVIDEIIS LESSYNDEML SYLPGGTTGL QLPSTLPVSG NLLDVYSSQG VATPAITVSN SCPAELPNIK REISETEAKA LLKERQKKDN HNLIERRRRF NINDRIKELG TLIPKSSDPE MRWNKGTILK ASVDYIRKLQ KEQQRSKDLE SRQRSLEQAN RSLQLRIQEL ELQAQIHGLP
Target Information
The activation of gene transcription is a multistep process triggered by factors recognizing transcriptional enhancer sites in DNA. These factors cooperate with co-activators to direct transcriptional initiation by RNA polymerase II.
The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, facilitates efficient activation by SP1. It is also a component of other multisubunit complexes, such as thyroid hormone receptor-associated proteins, which interact with TR and enable TR function on DNA templates.
This protein contains a bipartite nuclear localization signal and is known to escape chromosome X-inactivation.
Usage Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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