Thermo Fisher Scientific Btk Monoclonal Antibody
인간 BTK 단백질을 인식하는 Mouse IgG 단일클론 항체로, Western blot에 적합합니다. 비결합형 액상 형태이며 1 mg/mL 농도로 제공됩니다. K-562, Raji, THP-1 등 양성 샘플에서 검증되었으며, -20°C에서 보관합니다.
- 카탈로그번호
- MA537817
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
- Publications: [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | Recombinant protein of human BTK |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Product Specific Information
- Positive Samples: K-562, Raji, THP-1
Target Information
Bruton tyrosine kinase (BTK) is a cytoplasmic tyrosine kinase belonging to the SRC-related TEC subfamily of tyrosine kinases. Mutations in the BTK gene have been linked to severe developmental blocks in human B-cell ontogeny and immunodeficiency disorders.
BTK interacts with toll-like receptor (TLR) family members such as TLR4, 6, 8, and 9, which are essential in both innate and adaptive immunity. It also associates with key proteins involved in TLR4 signal transduction, including MyD88, TIRAP, and IRAK, but not TRAF-6, suggesting BTK’s role in lipopolysaccharide signal transduction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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