Thermo Fisher Scientific AADAT Polyclonal Antibody

Applications

Immunohistochemistry (Paraffin) [IHC (P)]

• Tested Dilution: 2.5 µg/mL

Product Specifications

Product Specific Information

• Percent identity with other species by BLAST analysis:
  Human, Gorilla, Gibbon, Elephant (100%); Monkey, Rabbit (94%); Marmoset, Dog (82%)
• For IHC(P), use heat-induced antigen retrieval in pH 6.0 citrate buffer.
  After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

Target Information

This gene encodes a protein highly similar to mouse and rat kynurenine aminotransferase II.
The rat protein is a homodimer with two transaminase activities:

1. Transamination of alpha-aminoadipic acid — final step in the saccharopine pathway (major pathway for L-lysine catabolism).
2. Transamination of kynurenine — produces kynurenine acid, precursor of kynurenic acid with neuroprotective properties.

Two alternative transcripts encoding the same isoform have been identified; additional variants may exist.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.