Thermo Fisher Scientific Phospho-PDGFRB (Tyr1021) Monoclonal Antibody (T.885.2)
Phospho-PDGFRB (Tyr1021) 단일클론 항체로, Western blot에 최적화되어 있습니다. 인간, 생쥐, 랫트 반응성을 가지며 rabbit IgG 유래입니다. 액상 형태로 친화 크로마토그래피 정제되었으며, -20°C에서 보관합니다. 연구용 전용 제품입니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | T.885.2 |
| Immunogen | Synthetic phosphopeptide corresponding to residues surrounding pTyr1021 of human PDGF receptor β |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage buffer | 0.01M HEPES (pH 7.5), 0.15M NaCl, 100µg/mL BSA, 50% glycerol |
| Contains | <0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_10981931 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
PDGFRB is a receptor tyrosine kinase implicated in atherogenesis and cell transformation by the SIS oncogene. These growth factors act as mitogens for cells of mesenchymal origin. The receptor composition (homo- or heterodimer) depends on the growth factor bound. The PDGFRB gene, located on chromosome 5, is flanked by genes for GM-CSF and M-CSF receptor, all possibly involved in the 5-q syndrome. A translocation between chromosomes 5 and 12 fusing PDGFRB (CD140b) with the ETV6 leukemia gene can result in chronic myeloproliferative disorder with eosinophilia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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