Thermo Fisher Scientific COX4 Monoclonal Antibody (K.473.4)
COX4 단백질을 인식하는 Rabbit monoclonal antibody (Clone K.473.4). Western blot, IHC, ICC, Flow cytometry 등 다양한 응용에 적합. 항원 친화 크로마토그래피로 정제된 고순도 항체로, -20°C 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 10 publications |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:2,000 | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:200–1:800 | View 3 publications |
| Flow Cytometry (Flow) | 1:400–1:1,600 | - |
| Immunoprecipitation (IP) | 1:100 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Human, Non-human primate, Pig, Rat, Zebrafish |
| Published Species | Human, Mouse, Non-human primate, Rat, Rhesus monkey |
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | K.473.4 |
| Immunogen | Synthetic peptide corresponding to residues surrounding Lys29 of human COX IV |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 331 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | <0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_10987478 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. COX4 (COX4I1) is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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