Thermo Fisher Scientific AK1 Monoclonal Antibody (OTI19G4), TrueMAB
AK1 단백질을 인식하는 마우스 단클론 항체로, Western blot 및 유세포분석에 적합합니다. 동결건조 형태로 제공되며, 재구성 후 약 1 mg/mL 농도로 사용 가능합니다. 인간 유래 단백질을 면역원으로 제작되었으며, 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI19G4 |
| Immunogen | Full length human recombinant protein of human AK1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Adenylate kinase (AK) regulates the adenine nucleotide composition within cells by catalyzing the reversible transfer of phosphate groups among adenine nucleotides.
Three isozymes have been identified in vertebrates: AK1, AK2, and AK3.
- AK1: Found in the cytosol of skeletal muscle, brain, and erythrocytes
- AK2, AK3: Located in mitochondria of tissues such as liver and heart
AK1 is associated with a rare genetic disorder, nonspherocytic hemolytic anemia, caused by mutations that reduce its catalytic activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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