Thermo Fisher Scientific NEUROG1 Monoclonal Antibody (OTI6C9), TrueMAB
인간 NEUROG1 단백질을 인식하는 Mouse monoclonal antibody로, WB, ICC/IF, IP에 적합합니다. 고순도의 Affinity chromatography 정제 제품이며, Lyophilized 형태로 제공됩니다. 신경발생 연구 및 세포 분화 조절 기전 연구에 활용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Immunoprecipitation (IP) | 2–4 µg/mg |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6C9 |
| Immunogen | Full-length human recombinant NEUROG1 protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, it is recommended to perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Neurogenin 1 (NEUROG1) is a basic helix-loop-helix (bHLH) transcription factor involved in cell fate determination during development. It plays dual roles in neurogenesis and inhibition of astrocyte differentiation. NeuroG1 promotes neuronal differentiation by acting as a transcriptional activator, while it inhibits astrocyte differentiation by preventing the CREB-binding protein transcription complex from activating astrocyte-specific genes and by suppressing STAT transcription factors essential for gliogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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