Thermo Fisher Scientific Synaptophysin Recombinant Rabbit Monoclonal Antibody (8H2L12)

Applications and Tested Dilution

Product Specifications

Product Specific Information

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. These systems are developed by cloning specific antibody DNA sequences from immunoreactive rabbits, followed by screening to select optimal clones for production.
Advantages include:

• Enhanced specificity and sensitivity
• Lot-to-lot consistency
• Animal origin-free formulation
• Broad immunoreactivity due to the larger rabbit immune repertoire

Target Information

Synaptophysin is a calcium-binding integral membrane glycoprotein located in presynaptic vesicles of nearly all neurons. It has four transmembrane domains and forms a complex with dynamin at high calcium concentrations, indicating a role in synaptic vesicle endocytosis.
It also contributes to the regulation of short- and long-term synaptic plasticity and is widely used as a marker for nerve terminals and neuroendocrine tumor differentiation.
Mutations in the synaptophysin gene have been associated with X-linked mental retardation 96.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.