Thermo Fisher Scientific CD62L (L-Selectin) Monoclonal Antibody (DREG-56 (DREG56)), APC, eBioscience
인간 CD62L(L-Selectin)에 특이적인 DREG-56 단클론 항체로, APC 형광체가 결합된 제품입니다. Flow Cytometry용으로 최적화되어 있으며 5 µL/test로 사용됩니다. 면역세포의 염증 부위 이동 및 림프절 호밍 연구에 적합합니다.
- 카탈로그번호
- 17-0629-42
- 판매단위
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Thermo Fisher Scientific CD62L (L-Selectin) Monoclonal Antibody (DREG-56 (DREG56)), APC, eBioscience
Applications
- Flow Cytometry (Flow)
Tested Dilution: 5 µL (0.5 µg)/test
Publications: View 20 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host/Isotype | Mouse / IgG1, kappa |
| Recommended Isotype Control | Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), APC, eBioscience™ |
| Class | Monoclonal |
| Type | Antibody |
| Clone | DREG-56 (DREG56) |
| Conjugate | APC |
| Excitation/Emission Max | 651/660 nm |
| Form | Liquid |
| Concentration | 5 µL/Test |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 0.2% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10671132 |
Additional Formats Available
- Unconjugated
- Alexa Fluor 532
- APC-eFluor 780
- Brilliant UV 496, 615, 737, 805
- Brilliant Violet 421, 480, 650, 711, 786
- eFluor 450
- FITC
- Functional Grade
- NovaFluor Blue 510, 555, 585, 610-30S, 660-40S, 690, 760
- NovaFluor Red 710, 725, 755
- NovaFluor Yellow 570, 590, 660
- PE, PE-Cyanine5, PE-Cyanine7, PE-eFluor 610
- PerCP-eFluor 710
- Super Bright 436, 600
- Request custom conjugation
Product Specific Information
The DREG-56 monoclonal antibody reacts with human CD62L, a 76 kDa member of the selectin family. CD62L is expressed by neutrophils, monocytes, and subsets of T, B, and NK cells. It binds glycosylated, fucosylated, and sulfated sialylated glycoproteins such as CD34, GlyCAM-1, and MAdCAM-1, mediating lymphocyte rolling on activated endothelium and homing to high endothelial venules (HEV) in peripheral lymphoid tissues.
Applications Reported: Flow cytometric analysis
Applications Tested: Pre-titrated and tested with normal human peripheral blood cells
- Recommended use: 5 µL (0.5 µg) per test
- Test volume: 100 µL
- Cell number: 10⁵–10⁸ cells/test
Excitation: 633–647 nm
Emission: 660 nm
Laser: Red Laser
Filtration: 0.2 µm post-manufacturing filtered
Target Information
Human CD62L (L-Selectin) is a 74–95 kDa glycoprotein, a member of the selectin family of adhesion receptors. It includes:
- Aminoterminal C-type lectin binding domain
- EGF-like domain
- Two short consensus repeat (SCR) sequences
- Transmembrane and cytoplasmic regions
CD62L is constitutively expressed on most leukocytes including lymphocytes (except many memory T cells), monocytes, and polymorphonuclear cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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