Thermo Fisher Scientific DFNA5 Polyclonal Antibody
Thermo Fisher Scientific의 DFNA5 Polyclonal Antibody는 인간 DFNA5 단백질을 인식하는 토끼 다클론 항체입니다. Western blot 및 ICC/IF에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human DFNA5 (Recombinant protein control fragment: Product #RP-102091) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2789587 |
Product Specific Information
Immunogen sequence:
VLFDDELLMV LEPVCDDLVS GLSPTVAVLG ELKPRQQQDL VAFLQLVGCS LQGGCPGPED AGSKQLFMTA YFLVSALAEM PDSAAALLGT CCKLQIIPTL CHLLRALSDD GVSDLEDPTL TPLKDTERFG IVQRLFASAD ISLERLKSSV
Target Information
DFNA5 (deafness, autosomal dominant 5), also known as ICERE-1, is a 496 amino acid protein expressed in cochlea tissue as well as in placenta, brain, heart, liver, lung, and pancreas. It exists as two alternatively spliced isoforms (short and long).
Defects in the DFNA5 gene cause non-syndromic sensorineural deafness autosomal dominant type 5 (DFNA5), a form of hearing loss due to damage in auditory structures.
The DFNA5 gene is located on human chromosome 7, which contains over 1,000 genes and represents about 5% of the human genome. Mutations in genes on chromosome 7 are associated with disorders such as Osteogenesis imperfecta, Williams-Beuren syndrome, Pendred syndrome, Lissencephaly, Citrullinemia, and Shwachman-Diamond syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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