Thermo Fisher Scientific Desmocollin 2 Polyclonal Antibody
Human Desmocollin 2 단백질을 인식하는 Rabbit Polyclonal Antibody. IHC(P)에서 1:200–1:500 희석으로 검증됨. 항원 친화 크로마토그래피로 정제된 액상 항체. 세포 간 접착 구조 연구 및 암 관련 단백질 발현 분석에 적합.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human DSC2. Recombinant protein control fragment (Product #RP-90653). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2789599 |
Product Specific Information
Immunogen sequence:
IGVVNEAPFS REASPRSAMS TATVTVNVED QDEGPECNPP IQTVRMKENA EVGTTSNGYK AYDPETRSSS GIRYKKLTDP TGWVTIDENT GSIKVFRSLD REAETIKNGI YNITVLASDQ GGRTCTGTLG IILQDVNDNS
Target Information
This gene encodes a member of the desmocollin protein subfamily. Desmocollins, along with desmogleins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress.
This gene is found in a cluster with other desmocollin family members on chromosome 18. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11, and reduced protein expression has been described in several types of cancer.
Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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