Thermo Fisher Scientific SAP102/DLG3 Polyclonal Antibody
SAP102/DLG3 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC, ELISA 등에 사용 가능. Human, Mouse, Rat 반응성. Protein A 정제, 1 mg/mL 농도, -20°C 보관. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human SAP102 (amino acids 501–600) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Synapse-Associated Protein 102 (SAP102) is a plasma membrane-associated protein found in synaptic junctions. It contains three PDZ domains, an SH3 domain, and a guanylate kinase homology (GuK) domain. SAP102 is involved in receptor and ion channel clustering, contributing to neuronal plasticity. It interacts with NMDA receptors and shaker-type potassium channels via PDZ-domain binding. Other neuronal proteins sharing the T/SXV motif, such as β1-adrenergic receptors and certain serotonin receptors, may also bind SAP102. Additionally, neuronal nitric oxide synthase (nNOS) can associate with SAP102 through PDZ–PDZ interactions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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