
Thermo Fisher Scientific Human IgE Chimeric Recombinant Isotype Control (TES-C21)
ELISA 및 억제 분석용 인간 IgE 키메릭 동형 대조항체. HEK293 세포에서 발현된 재조합 단클론 항체로, 비접합 액상 형태이며 1 mg/mL 농도. 단기 4°C, 장기 -20°C 보관 권장. 알레르기 연구 및 면역학적 분석에 적합.
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Applications
- ELISA (ELISA): Assay-dependent
- Inhibition Assays (IA): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Isotype Control |
| Clone | TES-C21 |
| Immunogen | Polyclonal human IgE |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C (short term). For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3074429 |
Target Information
IgE is one of the five classes of immunoglobulins found in mammals. Monomers consist of two heavy (epsilon) chains with four Ig-like constant domains, and two light chains. IgE plays an essential role in type I hypersensitivity (e.g., hay fever, asthma, hives, anaphylactic shock) by binding to Fc receptors on basophils and mast cells. Crosslinking of IgE bound to Fc receptors induces degranulation of mast cells and basophils, promoting allergic manifestations. IgE is also functionally important for immunity against parasites.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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