Thermo Fisher Scientific PCDHGC5 Monoclonal Antibody (OTI1G6), TrueMAB

Applications

Tested Application

• Western Blot (WB): 1:2,000 dilution

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, it is recommended to perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

The PCDHGC5 gene is part of the protocadherin gamma gene cluster located on chromosome 5. This cluster, along with the alpha and beta clusters, exhibits an immunoglobulin-like organization, suggesting a unique regulatory mechanism. The gamma cluster contains 22 genes divided into subfamilies A, B, and C.
Each variable region exon encodes an extracellular domain with six cadherin ectodomains and a transmembrane region, followed by constant region exons encoding a shared cytoplasmic region. These neural cadherin-like cell adhesion proteins are believed to play crucial roles in establishing and maintaining specific neuronal connections in the brain. Alternative splicing has been observed within the gamma cluster genes.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.