Thermo Fisher Scientific CCR10 Polyclonal Antibody
Rabbit polyclonal antibody against human CCR10, validated for WB and Flow applications. Recognizes human and mouse, predicted to react with monkey, bovine, and rabbit. Affinity purified, supplied as liquid in PBS with glycerol and BSA. For research use...
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–2 µg/mL | - |
| Flow Cytometry (Flow) | - | View 1 publication |
Product Specifications
| Category | Details |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptides corresponding to Human CCR10 (aa 14–29, 350–362) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 30% glycerol, 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2633253 |
Product Specific Information
These polyclonal antibodies are of rabbit origin, developed by immunizing animals with specific proteins or peptides. The antibody is purified by affinity chromatography from rabbit sera and tested for functionality in relevant research applications.
Developed for Research Use Only and classified as non-hazardous and non-infectious.
This antibody is predicted to react with Monkey, Bovine, and Rabbit.
Target Information
Chemokines are a group of small (approximately 8–14 kDa), mostly basic, structurally related molecules that regulate leukocyte trafficking through interactions with 7-transmembrane, G protein-coupled receptors.
They play essential roles in immune system development, homeostasis, and function, and influence cells of the CNS and endothelial cells involved in angiogenesis or angiostasis.
Chemokines are divided into two main subfamilies:
- CXC chemokines: first two conserved cysteines separated by one amino acid
- CC chemokines: first two conserved cysteines are adjacent
CCR10 is the receptor for CCL27; their interaction is involved in T cell-mediated skin inflammation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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