Thermo Fisher Scientific AGR2 Polyclonal Antibody
Rabbit polyclonal antibody targeting AGR2 protein for research use. Validated in WB and ICC/IF. Reacts with human, mouse, and rat. Affinity-purified, supplied as liquid in PBS with glycerol. Suitable for cancer and molecular marker research.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptides corresponding to Human AGR2 (31–44, 164–175) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 30% glycerol, 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at −20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2633250 |
Product Specific Information
These polyclonal antibodies are of rabbit origin, developed by immunizing animals with specific proteins or peptides. The antibodies are affinity-purified from rabbit sera and tested for functionality in relevant research applications.
They are intended for Research Use Only and are non-hazardous and non-infectious in nature.
This antibody is predicted to react with Monkey, Dog, Cat, and Bovine.
Target Information
AGR2 (anterior gradient protein 2) and AGR3 belong to the anterior gradient homolog family. These secreted cytoplasmic proteins are involved in metastasis induction and p53 tumor suppressor inhibition.
They may serve as molecular markers and potential therapeutic targets for hormone-responsive breast tumors.
AGR2 is widely expressed and upregulated in prostate, breast, lung, renal, and endometrial carcinomas. Its expression correlates positively with the estrogen receptor (ER) and negatively with the epidermal growth factor receptor (EGFR).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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