Thermo Fisher Scientific DR4 Monoclonal Antibody (DR-4-02), FITC
인간 TRAIL-R1 (DR4) 인식 단일클론 항체로, FITC 형광표지되어 유세포분석(Flow Cytometry)에 적합합니다. 498/517 nm 파장에서 여기/방출되며, 액상 형태로 제공됩니다. PBS(pH 7.4) + 0.2% BSA, 15mM sodium azide 포함, 4°C 암소 보관.
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Applications
Flow Cytometry (Flow)
- Tested Dilution: 3–5 µg/mL
- Publications: View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | DR-4-02 |
| Immunogen | Fusion protein containing the extracellular part of TRAIL-R1 and the constant part of the heavy chain of the human IgG1 |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Size-exclusion chromatography |
| Storage Buffer | PBS, pH 7.4, with 0.2% BSA |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1955203 |
Available Formats
Product Specific Information
This antibody recognizes an extracellular epitope of TRAIL-R1 (DR4), a human death receptor 4 expressed in most human tissues (spleen, peripheral blood leucocytes, thymus) and in a variety of tumor-derived cell lines.
Target Information
TRAIL-R1 (CD261, DR4) is a type I transmembrane protein, also called TRAIL receptor 1. The ligand for this DR4 death receptor has been identified and termed TRAIL, which is a member of the TNF family. DR4, as many other receptors (Fas, TNFR1, etc.), mediates apoptosis and NF kappaB activation in many cells and tissues. Apoptosis, a programmed cell death, is a key process in normal cellular differentiation and development of multicellular organisms, induced by cytokines (TNF family - TNF, Fas ligand) and their death domain-containing receptors (TNFR1, Fas receptor).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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