Thermo Fisher Scientific ULK2 Polyclonal Antibody
ULK2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 ELISA에 적합하며, 인간 및 랫트 반응성. 액상 형태로 제공되며, -20°C에서 보관. 자가포식 관련 연구에 활용 가능.
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Thermo Fisher Scientific ULK2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 1–100 of human ULK2 (NP_0011360821) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.03 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2806021 |
Product Specific Information
- Immunogen sequence: MEVVGDFEYS KRDLVGHGAF AVVFRGRHRQ KTDWEVAIKS INKKNLSKSQ ILLGKEIKIL KELQHENIVA LYDVQELPNS VFLVMEYCNG GDLADYLQAK
- Positive Samples: PC-3
- Cellular Location: Cytoplasmic vesicle membrane, Peripheral membrane protein
Target Information
ULK2 (also known as ATG1B) is a key serine/threonine protein kinase acting at the most upstream step of autophagosome formation. Knockout of ULK2 causes severe defects in autophagy. ULK2 is highly conserved among eukaryotes and shows high homology with ULK1. Both ULK1 and ULK2 form a complex with ATG13 and FIP200 that mediates TOR signaling and is essential for autophagy. ULK2 is also involved in early neuronal growth and differentiation.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-90315_ULK2_Q8IYT8-1_Rabbit.svg, PA5-90315_ULK2_Q8IYT8-1_Rabbit_PDP.jpeg)
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