Thermo Fisher Scientific Caspase 7 p11 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 150-250 of human Caspase-7 (NP_0012181) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Caspase 7 p11,uniProtId:P55210-1,ncbiNodeId:9606,antigenRange:150-250,antigenLength:303,antigenImageFileName:PA5-90312_Caspase_7_p11_P55210-1_Rabbit.svg,antigenImageFileNamePDP:PA5-90312_Caspase_7_p11_P55210-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.11 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2806019

Product Specific Information

Immunogen sequence: IYGKDGVTPI KDLTAHFRGD RCKTLLEKPK LFFIQACRGT ELDDGIQADS GPINDTDANP RYKIPVEADF LFAYSTVPGY YSWRSPGRGS WFVQALCSIL E

Positive Samples: 293T, Mouse liver, Mouse lung, Mouse intestine; Cellular Location: Cytoplasm

Target Information

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of this caspase is cleaved by caspase 3 and 10. It is activated upon cell death stimuli and induces apoptosis. Alternative splicing results in four transcript variants, encoding three distinct isoforms.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.