Thermo Fisher Scientific Phospho-BIK (Thr33) Polyclonal Antibody
인산화된 BIK(Thr33)을 특이적으로 인식하는 Rabbit Polyclonal Antibody. Western blot 및 IHC(P)에서 검증됨. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관. 세포 사멸 연구 및 항아폽토시스 단백질 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC(P)) | 1:50–1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide sequence around phosphorylation site of threonine 33 (G-M-T(p)-D-S) derived from Human BIK |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2607946 |
Target Information
The Bik protein interacts with cellular and viral survival-promoting proteins such as BCL2 and the Epstein-Barr virus to enhance programmed cell death. Its activity is suppressed in the presence of survival-promoting proteins, suggesting that it is a likely target for antiapoptotic proteins. Bik shares a critical BH3 domain with other death-promoting proteins, BAX and BAK.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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