Thermo Fisher Scientific Phospho-AKT1 (Tyr326) Polyclonal Antibody
Phospho-AKT1 (Tyr326) 항체로 인간, 마우스, 랫에서 반응하며 Western blot에 적합. 항원 친화 크로마토그래피로 정제된 비결합형 액상 항체. 세포 생존 및 신호전달 연구용으로 사용 가능. -20°C 보관, 동결-해동 반복 회피.
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Applications
- Western Blot (WB): 1:500–1:3,000
- View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide sequence around phosphorylation site of tyrosine 326 (N-D-Y(p)-G-R) derived from Human Akt |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2608973 |
Product Specific Information
This antibody is predicted to react with mouse and rat based on sequence homology.
Target Information
AKT1 (PKB alpha) is a serine/threonine kinase that regulates cell survival. The activated enzyme inhibits apoptosis and stimulates cell cycle progression by phosphorylating numerous targets in various cell types, including cancer cells. This protein kinase is activated by insulin, PI3K, IGF1 and various other growth and survival factors. Akt promotes cell survival by inhibiting apoptosis through phosphorylation and inactivation of several targets, including forkhead transcription factors and caspase-9. The AKT pathway is a major target for cancer drug discovery.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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