Thermo Fisher Scientific MFN2 Monoclonal Antibody (N153/5), FITC
MFN2 단백질을 인식하는 FITC 결합 단클론 항체로, Western blot, IHC, ICC/IF 등 다양한 응용에 적합. 인간, 생쥐, 랫드 반응성. 단백질 G 정제, 1 mg/mL 농도, 4°C 암소 보관. 미토콘드리아 융합 및 신경 질환 연구에 활용 가능.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific MFN2 Monoclonal Antibody (N153/5), FITC
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (IHC) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | N153/5 |
| Immunogen | Fusion protein amino acids 370–600 (cytoplasmic N-terminus) of mouse Mitofusin-2 |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | 9.1 mM sodium bicarbonate/PBS, pH 7.4, with 640.91 mM DMSO, 136.36 mM ethanolamine |
| Contains | No preservative |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2932124 |
Available Formats
- Unconjugated (MA5-27647)
- APC (MA5-45669)
- PE (MA5-45672)
- PerCP (MA5-45671)
- Custom conjugation available upon request
Product Specific Information
- Rat: 97% identity (226/231 amino acids identical)
- Human: 92% identity (214/231 amino acids identical)
- ~55% identity with Mitofusin-1
- 1 µg/mL of MA5-45670 detects Mitofusin-2 in 20 µg of mouse cardiac mitochondrial lysate by colorimetric immunoblot using Goat anti-mouse IgG:HRP as secondary antibody
- Detects approximately 90 kDa
- No cross-reactivity against Mitofusin-1
- Formerly sold as clone S153-5
Target Information
This gene encodes a mitochondrial membrane protein involved in mitochondrial fusion and maintenance of the mitochondrial network. It regulates vascular smooth muscle cell proliferation and may be implicated in obesity-related pathophysiology. Mutations cause Charcot-Marie-Tooth disease type 2A2 and hereditary motor and sensory neuropathy VI, both affecting the peripheral nervous system. Defects have also been linked to early-onset stroke. Two transcript variants encoding the same protein are known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.