
Thermo Fisher Scientific VDAC Monoclonal Antibody (N152B/23), APC
VDAC1 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, APC 형광 접합체를 사용합니다. 인간, 생쥐, 랫트 시료에 반응하며 WB, IHC, ICC/IF에 적용 가능합니다. 고순도 Protein G 정제, 4°C 보관 조건, 연구용으로 적합합니다.
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Thermo Fisher Scientific VDAC Monoclonal Antibody (N152B/23), APC
Applications and Tested Dilution
- Western Blot (WB): 1:1,000
- Immunohistochemistry (IHC): Assay-dependent
- Immunocytochemistry (ICC/IF): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | N152B/23 |
| Immunogen | Fusion protein amino acids 1–283 (full-length) of human VDAC1 |
| Conjugate | APC |
| Excitation / Emission Max | 651 / 660 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | 95.46 mM phosphate / 2.48 mM MES, pH 7.4, with 2M EDTA |
| Contains | No preservative |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2932120 |
Additional Formats
Product Specific Information
- Mouse: 98% identity (279/283 amino acids identical)
- Rat: 98% identity (279/283 amino acids identical)
60% identity with VDAC2 and VDAC3
- Detects approximately 30 kDa
- Does not cross-react with VDAC2 or VDAC3 (KO validation results)
- 1 µg/mL sufficient for detection of VDAC1 in 20 µg of rat brain lysate by colorimetric immunoblot using Goat anti-mouse IgG:HRP
- Formerly sold as clone S152B-23
Target Information
Voltage-dependent anion channel (VDAC) proteins are abundant pore-forming proteins located in the eukaryotic mitochondrial outer membrane and also expressed in the plasma membrane.
They play essential roles in cellular metabolism and apoptosis regulation, mediating metabolite exchange (ADP/ATP, succinate, citrate) between cytosol and mitochondria.
VDAC1 in the plasma membrane contributes to apoptosis regulation through its redox activity.
Usage
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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