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Thermo Fisher Scientific CACNA1S Polyclonal Antibody
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CACNA1S 단백질을 인식하는 Rabbit Polyclonal 항체로, Human, Mouse, Rat 시료에 반응합니다. Western blot 및 IHC에 사용 가능하며, n-terminal 합성 펩타이드를 면역원으로 제작되었습니다. 연구용으로만 사용 가능합니다.
- 판매단위
- pk
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563,100원VAT 포함 619,410원
Thermo Fisher Scientific · Thermo Fisher Scientific CACNA1S Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:1,000–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the N-terminal of human CACNA1S (Cav1.1) conjugated to blue carrier protein was used as the antigen. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
- The peptide is homologous in rat and mouse.
- Specificity: CACNA1S.
Target Information
Voltage-sensitive calcium channels mediate the entry of calcium into excitable cells and play a key role in neurotransmitter release and excitation-contraction (E-C) coupling.
1,4-dihydropyridines (DHPs) are synthetic organic compounds used to identify L-type calcium channels in vertebrate muscle, neuronal, and neuroendocrine cells.
The DHP receptor, part of the L-type calcium channel complex, acts as the voltage sensor in E-C coupling and consists of multiple subunits:
- Alpha-1 subunit: Contains the DHP binding site; homologous to voltage-gated sodium channels.
- Alpha-2 subunit: Large glycoprotein associated with the DHP receptor; found in skeletal, cardiac, and brain tissues.
- Beta and gamma subunits: Co-purify with the DHP receptor.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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