Thermo Fisher Scientific CAP-18 Polyclonal Antibody
Human CAP-18 단백질을 인식하는 Sheep 유래 Polyclonal 항체로, WB 및 IHC에 적합합니다. 동결건조 형태로 제공되며, 재구성 후 사용 가능합니다. Cathelicidin 항균 펩타이드 특이성을 가지며, 연구용으로만 사용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:100–1:2,000 |
| Immunohistochemistry (IHC) | 1:100–1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Sheep / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from aa region 40–80 of human CAP-18 conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Storage buffer | Whole serum |
| Contains | No preservative |
| Storage conditions | Store at 4°C short term. For long term, store at -20°C avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: Cathelicidin antimicrobial peptide.
Target Information
Cathelicidin is an epithelial-derived antimicrobial protein found in specific granules of polymorphonuclear leukocytes, bone marrow, testis, and neutrophils. Cathelicidins are a family of antimicrobial peptides characterized by conserved pro-peptide sequences identified in epithelial tissues and some myeloid cells of humans and animals.
LL-37/hCAP-18 is the only Cathelicidin found in humans and is expressed in inflammatory and epithelial cells. These molecules are essential for defense against invasive bacterial infection in skin. Besides direct antimicrobial activity, Cathelicidins mediate innate and adaptive immunity, including endotoxin neutralization, angiogenesis, wound healing, neutrophil chemotaxis, and mast cell recruitment.
Cathelicidin antimicrobial peptides are considered prototypes of innovative drugs for infection treatment and immune modulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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