Thermo Fisher Scientific CAP-18 Polyclonal Antibody
Thermo Fisher CAP-18 Polyclonal Antibody는 인간 Cathelicidin 항균 펩타이드에 특이적으로 반응하는 양 IgG 항체입니다. WB 및 IHC에 사용 가능하며, 동결건조 형태로 제공됩니다. 연구용으로만 사용되며 장기 보관 시 -20°C에서 안정적입니다.
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Applications
Western Blot (WB)
- Tested Dilution: 10–50 µg/mL
Immunohistochemistry (IHC)
- Tested Dilution: 10–50 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Sheep / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from aa region 40–80 of human CAP-18 conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Purification | Ammonium sulfate precipitation |
| Storage buffer | PBS |
| Contains | No preservative |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: Cathelicidin antimicrobial peptide.
Target Information
Cathelicidin is an epithelial-derived antimicrobial protein found in specific granules of polymorphonuclear leukocytes of bone marrow, testis, and neutrophils.
Cathelicidins are one family of antimicrobial peptides characterized by conserved pro-peptide sequences identified in epithelial tissues and some myeloid cells of humans and animals.
LL-37/hCAP-18 is the only Cathelicidin found in humans and is expressed in inflammatory and epithelial cells.
These molecules are essential for defense against invasive bacterial infection in skin.
Besides their direct antimicrobial function, Cathelicidins have multiple roles in mediating innate and adaptive immunity, such as endotoxin neutralizing, angiogenesis, wound healing, and promoting neutrophil chemotaxis and mast cell recruitment.
Cathelicidin antimicrobial peptides qualify as prototypes of innovative drugs that may be used to treat infection and/or modulate the immune response.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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