Thermo Fisher Scientific INPP5J Polyclonal Antibody
INPP5J 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Rabbit IgG 기반 액상 시약입니다. Human, Horse, Pig 등 다양한 종에 반응하며, IHC(P) 실험에 최적화되어 있습니다. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공합니다.
- 카탈로그번호
- PA532875
- 판매단위
- pk
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Applications
- Immunohistochemistry (Paraffin) [IHC (P)]: 10–15 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Horse, Human, Pig |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 19 amino acid peptide from internal region of human INPP5J / PIB5PA |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550336 |
Product Specific Information
Percent identity with other species by BLAST analysis:
- 100%: Human, Gorilla, Monkey, Elephant, Horse, Pig
- 95%: Gibbon, Marmoset, Mouse, Rat, Bovine, Dog, Hamster, Panda, Rabbit
- 89%: Bat, Platypus
For IHC(P), use heat-induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
Target Information
Inositol and phosphatidylinositol phosphates are crucial for numerous cellular processes, including neuronal survival and signal transduction from growth factors, neurotransmitters, and G protein-coupled receptors.
INPP5J (inositol polyphosphate-5-phosphatase J), also known as phosphatidylinositol 4,5-bisphosphate 5-phosphatase A, PIPP, PIB5PA, or INPP5, is a 1,006 amino acid cytoplasmic protein that assists in the conversion of inositol 1,4-bisphosphate from inositol 1,4,5-trisphosphate.
Expressed in lung, stomach, kidney, brain, small intestine, and heart, INPP5J localizes to membrane ruffles, where it may also participate in modulating inositol and phosphatidylinositol polyphosphate-binding proteins.
Encoded by a gene located on human chromosome 22, INPP5J undergoes alternative splicing to produce three isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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