Thermo Fisher Scientific Phospho-BLK (Tyr501) Polyclonal Antibody
인간 BLK 단백질의 Tyr501 인산화 부위를 인식하는 rabbit polyclonal antibody. IHC(P)에서 1:50~1:100 희석으로 사용 가능. 액상 형태로 PBS/glycerol buffer에 보관하며 -20°C에서 안정적. 연구용으로 B-cell 활성화 관련 신호전달 연구에 적합.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide sequence around phosphorylation site of tyrosine 501 (R-Q-Y(p)-E-L) derived from Human BLK |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2554101 |
Product Specific Information
- A suggested positive control for IHC is human breast carcinoma.
Target Information
B-lymphoid tyrosine kinase (BLK) is a non-receptor tyrosine kinase that belongs to the Src family of kinases.
BLK plays an important role in B-cell activation.
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the γ phosphate of ATP, onto an acceptor amino acid in a substrate protein.
By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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